On Tuesday, shortly after touching down in Washington, DC for his first meeting with President Trump, Prime Minister Benjamin Netanyahu invited Tillerson to visit Israel in the near future to continue their discussions on pressing matters such as Iran. Tillerson's participation at a meeting of foreign ministers from the Group of 20 major world economies is in some aspects his introductory foray into the world of diplomacy and its practitioners.
German Foreign Minister Sigmar Gabriel will host the meeting.
The first meeting between Tillerson and Lavrov comes amidst growing criticism from United States lawmakers over the Trump administration's relationship with Russian Federation.
They are likely to discuss the crisis in Syria.
Zakharova said Lavrov will "discuss bilateral relations, which were taken into a dead end by the previous administration".
President Trump has said "only "stupid" people" don't want a good relationship with Russian Federation and signaled during his presidential campaign that he was open to warmer relations with Moscow.
Lavrov welcomed Tillerson's nomination back in December: "We expect that this pragmatism will be a good foundation for building mutually beneficial cooperation", he said.